CHEM Seminar - Chemical Biology of Protein Aggregation in the Stressed Proteome
10:30am - 12:00pm
Room 6602, 6/F (Lifts 31/32), Academic Building, HKUST

Speaker: Professor Xin ZHANG


Institution: Department of Chemistry, Pennsylvania State University


Hosted by: Professor Benzhong TANG


 


Abstract


We are fosucsed on protein misfolding and aggregation that occur in stressed cells with deficient proteostasis. These molecular events have been associated with a variety of diseases that are termed as protein misfolding diseases. Protein aggregation is a multiple step process that involves misfolded soluble and insoluble aggregates. It is unclear which of these conformations could lead to cytotoxicity that is associated with diseases. In this seminar, I will describe how we have developed chemical methodologies that allow the community to visualize and differentiate, in live cells, the many conformations through the process of protein aggregation.

When
Time
10:30am - 12:00pm
Where
Room 6602, 6/F (Lifts 31/32), Academic Building, HKUST
Event Format
Speakers / Performers:
Professor Xin ZHANG
Department of Chemistry, Pennsylvania State University
Language
English
Recommended For
Faculty and Staff
PG Students
Organizer
Department of Chemistry
Contact
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